Iintshayelelo
Izinto ezintathu ze-myocardial infarction: Troponin I / Creatine Kinase Isozyme / Myoglobin (cTnI / CKMB / myo) Ikhithi yoVavanyo
I-Fluorescence immunochromatography
Ukubaluleka kweklinikhi
I-Myoglobin yeyona protein yokuqala ye-myocardial eyonyuka ngokungaqhelekanga emva komonakalo we-myocardial. I-serum myo iqala ukunyuka kwiiyure ezi-2 emva kokuhlaselwa kwe-myocardial acute kwaye ifikelele kwincopho kwiiyure ezingama-4-6. Ekubeni i-myo ayinayo inkcazo ye-myocardial, i-negative ye-myoglobin inceda
ngaphandle kokuxilongwa kwe-AMI. Esona sicwangciso silungileyo sokusebenzisa esi siphawuli kukusebenzisa ixabiso layo eliphezulu elibi lokuxela kwangaphambili kunye novakalelo lokulawula i-myocardial infarction.
I-Troponin I okwangoku isalathisi esithembekileyo sokuxilongwa kwe-myocardial infarction kunye neyona nto iphezulu kunye nexesha elide kakhulu. I-troponin ye-cardiac iyanda ngokuthe ngcembe kwi-periphery 4-8 iiyure emva kokulimala kwe-myocardial, kwaye ixabiso eliphezulu livela kwiiyure ze-12-24. I-troponin ye-cardiac ephakamileyo ingabonwa kwigazi le-peripheral 7-10 iintsuku emva kokulimala kwe-myocardial.
I-Creatine kinase isoenzyme okwangoku "yeyona mgangatho wegolide" wovavanyo lwe-AMi abathembela kuyo oogqirha kakhulu, kwaye inomgangatho ophezulu. Ukuxilongwa okudibeneyo kwe-cardiac troponin I (cTnI), i-creatine kinase isoenzyme (CKMB) kunye ne-myoglobin (myo) inobuzwe obungcono kunye neenkcukacha, okwenza ukuxilongwa kuchaneke ngakumbi. Ukufezekisa ukuxilongwa kwangaphambili, unyango lwakwangoko, ukunciphisa uxilongo oluphosiweyo kunye nokuhlelwa komngcipheko kwangethuba kwizigulana.
Imvelisoiinkcukacha
Inzuzo yemveliso:
Uvakalelo oluphezulu: i-cTnI Ngaphantsi okanye ilingana no-0.1 ng/mL; I-CKMB Ngaphantsi okanye ilingana no-0.1 ng/mL; Myo Ngaphantsi okanye ilingana no 2.5 ng/mL
Uluhlu olubanzi lomgca: cTnI (0.1-30 ng / mL); I-CKMB (1- 60 ng/mL); I-Myo (5-400 ng/mL)
Ixesha lokuphendula ngokukhawuleza: 15 min
Ixesha lokubona ngokukhawuleza: 7 s
Iiparamitha zokusebenza:
Uhlobo lwesampuli: i-serum, iplasma kunye negazi elipheleleyo
Ukuchaneka: I-CV Ngaphantsi okanye ilingana ne-15%
Ixabiso lokubhekisela: cTnI＜0.3 ng/mL; CKMB＜5 ng/mL; Myo＜55 ng/mL
Uvavanyo lokuthelekisa: Ukufunyanwa kwe-cTnI kunye ne-Beckman Chemiluminescence, ulungelelwaniso lwe-R2
ukufikelela kwi-0.9779; Unxulumano lwe-R² lwe-CKMB lufikelele kwi-0.9866; Unxulumano R² lweMyo lufikelelwe
0.9835
Isicelo seklinikhi:
I-acute myocardial infarction
Ukwenzakala kwamathambo
I-angina pectoris engazinzanga
Ukulimala kwe-Myocardial
Polymyositis
I-Rhabdomyolysis
Amasebe asetyenzisiweyo
Isebenza kwisebe le-cardiology, isebe likaxakeka, ibhubhoratri, utyando, izifo zabantwana, i-oncology, iyunithi yokunyamekela, i-ICU), i-hematology kunye namanye amasebe.
FAQ
Q: Yintoni le khithi yovavanyo kathathu, kwaye yintoni inzuzo yayo ephambili?
A: Ikiti yethu yoVavanyo oluKhawulezayo lwe-Triple Cardiac Marker sisixhobo sokuxilonga{0}} edge in vitro elinganisa ngaxeshanye nangobungakanani i-biomarker ezintathu ezibalulekileyo ze-Acute Myocardial Infarction (AMI): I-Cardiac Troponin I (cTnI), i-Creatine Kinase Isoenzyme MB (CK{1}MB) kunye neMbin (MB) Inzuzo ephambili kukufumana iprofayili yenhliziyo ebanzi kwisampuli enye kuvavanyo nje olunye, inceda kakhulu ekuxilongeni ngokukhawuleza nangokuchanekileyo kokuhlaselwa yintliziyo.
Umbuzo: Kutheni kubalulekile ukuvavanyelwa omathathu amanqaku (cTnI, CK{{0}MB, neMyoglobin) kubalulekile?
A: I-biomarker nganye ibonelela ngolwazi olulodwa, oluxhasayo kunye namaxesha ahlukeneyo okukhupha:
I-Myoglobin: Inyuka kuqala (ngaphakathi kwe-1{1}}iyure ezi-3), igqwesile kulawulo lwakwangoko ngenxa yexabiso layo eliphezulu elibi.
CK-MB: Inyuka ngaphakathi kwe-3-iiyure ezi-6 kwaye ingaphezulu kwentliziyo-ingakumbi kunemyoglobin. Iluncedo ekubhaqeni i-infarction kwakhona.
cTnI: "Umgangatho wegolide" wokuxilongwa kwe-AMI. Iphakama phakathi kweeyure ze-3-6 kwaye ihlala iphakanyisiwe iintsuku, inika ukuchaneka okuphezulu kumonakalo wemisipha yenhliziyo.
Ukuvavanya zonke zontathu kunye zigubungela yonke ifestile yokuxilongwa kwangaphambili kwaye iphucula ukuzithemba kweklinikhi.
Umbuzo: Ngaba uyabonelela nge-fluorescence immunoassay analyzer?
A: Ewe, sibonelela nge-compact,-enobuhlobo, kunye nezihlalutyi eziphathwayo zefluorescence immunoassay. Kukho itshaneli enye kunye ne-12-abahlalutyi bamajelo. Zibonisa ugcino lwedatha, ukhetho loqhagamshelo, kunye nokusebenza okulula, oko kuyenza ilunge kuzo zombini iilabhoratri kunye nendawo{5}}yokusetyenziswa kwenkathalo. Nceda ubhekisele kwiinkcukacha zethu zemveliso kuluhlu lwemveliso.
Iifayile ezishisayo: ctni / ck-mb / ikiti yovavanyo lwemyo, iChina ctni / ck-mb / abavelisi bekhithi yovavanyo lwemyo, ababoneleli
